Carboprost

Carboprost
Systematic (IUPAC) name
(5Z,9α,11α,13E,15S)-9,11,15-trihydroxy-15- methylprosta-5,13-dien-1-oic acid
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a600042
Pregnancy cat. c
Legal status Prescription only
Routes Intravenous
Identifiers
CAS number 58551-69-2 Y
ATC code G02AD04
PubChem CID 5281075
DrugBank APRD00847
ChemSpider 4444532 Y
UNII U4526F86FJ Y
ChEMBL CHEMBL1201299 N
Chemical data
Formula C21H36O5 
Mol. mass 368.508 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Carboprost (INN, trade names for the tromethamine salts Hemabate, Tham) is a synthetic prostaglandin analogue of PGF (specifically, it is 15-methyl-PGF) with oxytocic properties.

Carboprost induces contractions and can trigger abortion in early pregnancy. It also reduces postpartum bleeding.

Contents

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Indication

Used in postpartum hemorrhage caused by uterine atony not controlled by other methods.
Unlabeled use:

Contraindication

Contraindicated in severe cardiovascular, renal, and hepatic disease, also contraindicated in Pelvic Inflammatory Disease. Exert caution in asthmatic patients.

Precautions

Adverse Effects

References

External links